Basic Info.
Application
Food, Health Care Products, Medicine
State
Orange Yellow Powder
Extract Source
Root
Payment
T/T in Advance
Shelf Life
24 Months
Delivery Time
3-5 Working Days
Free Sample
Available
Transport Package
25kg/Cardboard Drum I. D. 42cm X H. 52cm
Specification
10%-80% Rhein 98% Rhein 98% Chrysophanol
Trademark
Shanghai, China
Origin
China
HS Code
13021990
Production Capacity
20 Ton/Month
Product Description
Product Profile
Rhubarb extract is the dried root and rhizome extract of the Polygonaceae plant Rheum palmata, Rhubarb tangut or medicinal rhubarb. Rhubarb tastes bitter and cold, and returns to the stomach, liver and large intestine meridian. The active ingredients are anthraquinone compounds, including rhein and rhubarb. Emodin, chrysophanol, aloe-emodin, emodin methyl ether, etc., have the effects of scavenging oxygen free radicals, regulating blood lipids, anti-arteriosclerosis, anti-cancer, anti-aging, anti-psychotic, anti-bacterial and anti-inflammatory, hepatoprotective, choleretic, and anti-viral.
Function
1. Effect on digestive system
1.1. Purgative effect:
The main site of diarrhea is in the large intestine. The active ingredient in rhubarb diarrhea is anthracene glycosides, mainly sennosides. Sennoside is decomposed under the action of intestinal bacterial enzymes to produce anthrone rhein, which can stimulate the large intestinal mucosa, increase intestinal peristalsis and cause diarrhea. In addition, it can inhibit Na+ and K+-ATPase on the intestinal cell membrane, hinder Na+ transport, increase intestinal osmotic pressure, retain a large amount of water, promote intestinal peristalsis and diarrhea.
1.2. Choleretic and hepatoprotective effects:
Rhubarb extract can promote bile secretion, increase the content of bilirubin and bile acids in bile, relieve bile sphincter spasm, enhance duodenal and bile duct relaxation, and clear bile stasis in bile ducts and tiny bile canaliculi.
2. Effect on blood system
2.1. Hemostatic effect:
The hemostatic effect of rhubarb extract is precise and effective. The active ingredients are α-catechin and gallic acid. The mechanism of action is to promote the adhesion and aggregation of platelets; increase the number of platelets and fibrinogen content; reduce the activity of antithrombin III; and constrict the blood vessels in the injured area.
2.2. Blood lipid lowering effect:
Rhubarb extract reduces total cholesterol, triacylglycerols, low-density lipoprotein, very low-density lipoprotein, and lipid peroxidation levels. Making rhubarb into granules and taking it for 2 months showed a good lipid-lowering effect and no adverse reactions.
2.3. Blood-activating effect:
Rhubarb extract has a blood dilution effect, which may be due to the plasma osmotic pressure effect, which promotes the transfer of extracellular fluid into blood vessels, thereby diluting the blood, resulting in a decrease in blood cells, a decrease in blood viscosity, thereby enhancing microcirculation and achieving the purpose of promoting blood circulation. .
3. Anti-infection effect
Rhubarb extract has inhibitory effects on a variety of Gram-positive and -negative bacteria in vitro, and is especially sensitive to Paratyphoid and Shigella dysenteriae. It also has a certain killing effect on hepatitis B virus, various fungi, amoeba, and Trichomonas vaginalis. The main antibacterial ingredients are rhein, emodin and aloe-emodin. The antibacterial mechanism mainly inhibits the oxidation and dehydrogenation of bacterial sugar metabolism intermediates, inhibits the synthesis of proteins and nucleic acids, inhibits bacterial biological oxidase systems, and induces interferons.
4. Antipyretic effect
In the acute phase of acute or infectious diseases, the application of rhubarb extract treatment can have a cooling effect, and the cooling effect is stable, without adverse reactions such as sweating or collapse. Its antipyretic mechanism is to inhibit the synthesis of prostaglandin E in the body temperature center, reduce the content of cyclic glycoside nucleic acid, expand peripheral blood vessels and increase heat dissipation to achieve the purpose of cooling.
5. Immunomodulatory effect
Rhubarb extract has a two-way regulatory effect on immune function. It has varying degrees of immunosuppression. It has inhibitory or blocking effects on cellular immunity and humoral immunity. Long-term use can cause damage to the thymus, spleen, lymph nodes and other immune organs. shrink. In addition, rhubarb can increase the phagocytosis of mouse peritoneal macrophages, promote the body's production of interferon, and improve immunity, thereby achieving the purpose of eliminating viruses.
6. Other functions
The tannins contained in rhubarb have good antioxidant effects. Rhubarb polysaccharide also has obvious inhibitory effects on tumors, as well as lowering blood lipids, diuresis, anti-inflammatory effects, and antihypertensive effects.
Certificates of Analysis
Rhubarb extract is the dried root and rhizome extract of the Polygonaceae plant Rheum palmata, Rhubarb tangut or medicinal rhubarb. Rhubarb tastes bitter and cold, and returns to the stomach, liver and large intestine meridian. The active ingredients are anthraquinone compounds, including rhein and rhubarb. Emodin, chrysophanol, aloe-emodin, emodin methyl ether, etc., have the effects of scavenging oxygen free radicals, regulating blood lipids, anti-arteriosclerosis, anti-cancer, anti-aging, anti-psychotic, anti-bacterial and anti-inflammatory, hepatoprotective, choleretic, and anti-viral.
Function
1. Effect on digestive system
1.1. Purgative effect:
The main site of diarrhea is in the large intestine. The active ingredient in rhubarb diarrhea is anthracene glycosides, mainly sennosides. Sennoside is decomposed under the action of intestinal bacterial enzymes to produce anthrone rhein, which can stimulate the large intestinal mucosa, increase intestinal peristalsis and cause diarrhea. In addition, it can inhibit Na+ and K+-ATPase on the intestinal cell membrane, hinder Na+ transport, increase intestinal osmotic pressure, retain a large amount of water, promote intestinal peristalsis and diarrhea.
1.2. Choleretic and hepatoprotective effects:
Rhubarb extract can promote bile secretion, increase the content of bilirubin and bile acids in bile, relieve bile sphincter spasm, enhance duodenal and bile duct relaxation, and clear bile stasis in bile ducts and tiny bile canaliculi.
2. Effect on blood system
2.1. Hemostatic effect:
The hemostatic effect of rhubarb extract is precise and effective. The active ingredients are α-catechin and gallic acid. The mechanism of action is to promote the adhesion and aggregation of platelets; increase the number of platelets and fibrinogen content; reduce the activity of antithrombin III; and constrict the blood vessels in the injured area.
2.2. Blood lipid lowering effect:
Rhubarb extract reduces total cholesterol, triacylglycerols, low-density lipoprotein, very low-density lipoprotein, and lipid peroxidation levels. Making rhubarb into granules and taking it for 2 months showed a good lipid-lowering effect and no adverse reactions.
2.3. Blood-activating effect:
Rhubarb extract has a blood dilution effect, which may be due to the plasma osmotic pressure effect, which promotes the transfer of extracellular fluid into blood vessels, thereby diluting the blood, resulting in a decrease in blood cells, a decrease in blood viscosity, thereby enhancing microcirculation and achieving the purpose of promoting blood circulation. .
3. Anti-infection effect
Rhubarb extract has inhibitory effects on a variety of Gram-positive and -negative bacteria in vitro, and is especially sensitive to Paratyphoid and Shigella dysenteriae. It also has a certain killing effect on hepatitis B virus, various fungi, amoeba, and Trichomonas vaginalis. The main antibacterial ingredients are rhein, emodin and aloe-emodin. The antibacterial mechanism mainly inhibits the oxidation and dehydrogenation of bacterial sugar metabolism intermediates, inhibits the synthesis of proteins and nucleic acids, inhibits bacterial biological oxidase systems, and induces interferons.
4. Antipyretic effect
In the acute phase of acute or infectious diseases, the application of rhubarb extract treatment can have a cooling effect, and the cooling effect is stable, without adverse reactions such as sweating or collapse. Its antipyretic mechanism is to inhibit the synthesis of prostaglandin E in the body temperature center, reduce the content of cyclic glycoside nucleic acid, expand peripheral blood vessels and increase heat dissipation to achieve the purpose of cooling.
5. Immunomodulatory effect
Rhubarb extract has a two-way regulatory effect on immune function. It has varying degrees of immunosuppression. It has inhibitory or blocking effects on cellular immunity and humoral immunity. Long-term use can cause damage to the thymus, spleen, lymph nodes and other immune organs. shrink. In addition, rhubarb can increase the phagocytosis of mouse peritoneal macrophages, promote the body's production of interferon, and improve immunity, thereby achieving the purpose of eliminating viruses.
6. Other functions
The tannins contained in rhubarb have good antioxidant effects. Rhubarb polysaccharide also has obvious inhibitory effects on tumors, as well as lowering blood lipids, diuresis, anti-inflammatory effects, and antihypertensive effects.
Certificates of Analysis
| Product Name: | Rheum Extract | Latin name | Rhubarb Extract | ||
| Part used: | Root | Country of origin | China | ||
| Item | Specification | Result | |||
| Assay | 20% Rhein | HPLC | |||
| Physical & Chemical | |||||
| Appearance | Orange yellow powder | Conforms | |||
| Odor & Taste | Characteristic | Characteristic | |||
| Particle Size | 90% through 80 mesh | Conforms | |||
| Loss on Drying | ≤5.0% | 1.32% | |||
| Ash | ≤5.0% | 2.11% | |||
| Heavy metals | |||||
| As | ≤2ppm | Conforms | |||
| Lead (Pb) | ≤2ppm | Conforms | |||
| Cadmium(Cd) | ≤1ppm | Conforms | |||
| Microbiological Test | |||||
| Total Plate Count | NMT 1000cfu/g | Conforms | |||
| Total Yeast & Mold | NMT 100cfu/g | Conforms | |||
| E.Coli | Negative | Negative | |||
| Salmonella | Negative | Negative | |||
| Pesticide Residue | Negative | Negative | |||
